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A new weight-loss drug that contains anti-addiction drug naltrexone has been approved by the U.S. Food and Drug Administration today, the company said in a very statement.

Using two separate drugs to lose weight naturally can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err on the side of caution and allow the FDA do its job and demand some research be done so the public understands the side effects and risks of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on his or her medications.

Researchers found that participants using this drug for the year, lost weight within 4 weeks and have kept the body weight off throughout the 56 weeks in the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, that might make them more efficient and safer.

Combo-pilling could be the newest fad or better yet the newest to come under scrutiny and so it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that at the time of right now there aren't any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise blood pressure levels and heartbeat, and really should not be used in people who have a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure levels and heartrate and must 't be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.


Suboxone is made up of two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if the tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone is utilized correctly, the naloxone is destroyed within the liver after that uptake in the intestines and contains no therapeutic effect. Buprenorphine may be the active substance; it is absorbed within the tongue (and during the entire mouth) but destroyed from the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation if the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I in addition have treated addicts who have had gastric bypass, in which the first section of the intestine is bypassed and the stomach contents empty right into a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the task with normal anatomy the location where the drug is taken up through the duodenum and transferred straight to the liver from the portal vein, where it really is quickly and completely destroyed. After gastric bypass naloxone can be taken up by areas of the intestine that aren't served from the portal system, causing blood numbers of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.

#1661 by achieveclimax

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